What is a great program(s) to make my computer run like new?

Barring a total reinstall, what are some cleaner programs that will help me make my computer run as smoothly as possible?
Answer #1
CCleaner
Avira Antivirus
MalwareBytes
Combofix
and a recovery CD and a Hirens Boot CD.
Answer #2
^ those and either Advanced SystemCare or TuneUp Utilities
Answer #3
deepfridge
Answer #4
No software is as good as a hardware.
A solid state drive, your system will boot up consistently fast and be very smooth.
Really makes all those software’s look like garbage.
Answer #5
http://www.piriform.com/ccleaner
http://www.piriform.com/defraggler
Answer #6
CCleaner and TuneUp
Answer #7
Slimcomputer & Slimcleaner work great.
https://www.slimwareutilities.com
Answer #8
ccleaner, RegClean Pro, Registry Smoker, & 7Smoker Pro. Thats all I use
Answer #9
Nothing will be as good as a clean install.